Why the study?
Does propranolol alter coronary artery diameter and vascular resistance during exercise in dogs?
Does propranolol alter coronary artery diameter and vascular resistance during exercise in dogs?
Beta-adrenoceptors are essential for exercise-induced dilation of large coronary arteries, whereas their activation only partially mediates the decrease in coronary vascular resistance during exercise.
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Animal data suggest beta-blockade impairs coronary dilation; leaves open relevance to human exercise physiology.
Berdeaux et al. (1991) studied this question.
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