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The two rat proinsulins have been separated and the amino acid compositions determined. Using a method previously described for preparing C-peptides from ox and pork pancreases, three peptides were isolated from rat pancreases and the amino acid compositions of these peptides determined. Data are presented which strongly indicate that two of these peptides constitute the C-peptide part of the connecting peptide of the two rat proinsulins.
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Sundby et al. (1972) studied this question.
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