Key result
Fascia iliaca compartment block with ropivacaine and dexmedetomidine significantly reduced pain during positioning for spinal anesthesia compared to ropivacaine alone (VAS 4.03 vs 4.93, p<0.0001).
Why the study?
The study was designed to compare ultrasound-guided fascia iliaca compartment block using ropivacaine alone versus ropivacaine plus dexmedetomidine for positioning during spinal anesthesia in femur fracture surgery.
Does the addition of dexmedetomidine to ropivacaine in fascia iliaca compartment block improve analgesia during positioning for spinal anesthesia in patients with femur fractures?
RCT (n=60)
Computer generated random table
Yes
Does the addition of dexmedetomidine to ropivacaine in fascia iliaca compartment block improve analgesia during positioning for spinal anesthesia in patients with femur fractures?
Absolute Event Rate: 4.03% vs 4.93%
p-value: p=<0.0001
The addition of dexmedetomidine to ropivacaine in ultrasound-guided fascia iliaca compartment block significantly improves analgesia during patient positioning for spinal anesthesia and prolongs the duration of postoperative pain relief in femur fracture surgeries.
May support dexmedetomidine adjunct in fascia iliaca blocks for femoral fractures; leaves open need for randomized human trials.
Introduction: Patients encountered with fracture shaft and neck femur require some anaesthesia or pain relief to allow radiological, orthopedic and other procedures to be performed. Regional anaesthesia is the most widely used an aesthetic technique for orthopedic procedures in lower limbs.Fascia iliaca blocks provide a safe, cheap and effective form of pain relief for patients with neck of femur fractures. Animal studies have proven the combination of dexmedetomidine with ropivacaine to be safe and neuro-protective. Fascia iliaca compartment block which involve femoral nerve, lateral cutaneous nerve of thigh and obturator nerve. This study is designed to compare Fascia Iliaca Compartment Block under ultrasound guidance with ropivacaine and ropivacaine plus dexmedetomidine positioning during spinal anesthesia in femur fractures. Material and methods: This study was conducted at Mahatma Gandhi hospital and Mathuradas Mathur hospital, Jodhpur during January 2019–January 2020. 60 Patients admitted in Orthopaedic ward age group 21-60 yrs. of both sex were the source of data. Patients undergoing elective surgery for fracture femur (neck of femur and intertrochanteric) under SAB were included in the study. We divided the cases into 2 groups of 30 each, as GROUP R: Patients were received 30 ml 0.50% Inj. ropivacaine + 2 ml Normal saline with a total volume of 32 ml in unilateral FICB. GROUP RD: Patients were received 30 ml 0.50% Inj. Ropivacaine + 2 ml Inj. Dexmeditomidine (0.5mcg/Kg) with a total volume of 32 ml in unilateral FICB. Standard protocol followed to administering regional anaesthesia. All data were collected and analysed with the help of suitable statistical parameters. Results: Our study results in that Fascia Iliaca Compartment Block with combination of ropivacaine and dexmedetomidine is more efficacious than ropivacaine alone for positioning during spinal anaesthesia in surgery for fracture femur.
No takes yet. Share an insight, caveat, or question.
Rajpurohit et al. (2021) conducted an RCT in Unilateral femur fracture (n=60). Ropivacaine and Dexmedetomidine vs. Ropivacaine alone was evaluated on Visual Analogue Scale (VAS) score during positioning at 5 minutes (p=<0.0001). Fascia iliaca compartment block with ropivacaine and dexmedetomidine significantly reduced pain during positioning for spinal anesthesia compared to ropivacaine alone (VAS 4.03 vs 4.93, p<0.0001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: