Key result
Among obese women, the presence of both polycystic ovary syndrome and metabolic syndrome was associated with a significantly higher body mass index (33.56 vs 31.97 kg/m2) compared to metabolic syndrome alone.
Why the study?
Polycystic ovary syndrome carries a high prevalence of metabolic syndrome and long-term cardiovascular risks, with worldwide prevalence often linked to obesity and type 2 diabetes mellitus but subject to regional variations.
Cross-Sectional (n=122)
No
Women with polycystic ovary syndrome and metabolic syndrome exhibit a high burden of cardiometabolic risk factors, including severe obesity, insulin resistance, and atherogenic dyslipidemia, highlighting the need for comprehensive metabolic screening.
Women with polycystic ovary syndrome (PCOS) have a high prevalence of metabolic syndrome (MS), with rates up to 33%.This is associated with long-term consequences such as cardiovascular diseases, type 2 diabetes mellitus (T2DM), cancer, sleep apnea, and psychological issues.The prevalence of MS worldwide is often associated with obesity and T2DM, yet regional variations are reported.In this study, 122 women consulting general practice and family medicine physicians were evaluated, revealing a BMI exceeding 30 kg/m².Among MS criteria, the most common diagnoses were T2DM in 29 patients, insulin resistance (IR) in 36, arterial hypertension (AH) in 51, reduced HDL levels in 53, and elevated triglycerides in 39.Further analysis revealed 16 unique combinations of MS components in these patients, with 75% of PCOS cases exhibiting three MS components and 25% having four.Additionally, research indicated that most women with PCOS face persistent, treatment-resistant obesity, with a notably higher BMI (ρ=0.87;r=0.76).These findings highlight the multifactorial nature of PCOS and MS etiology.
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Lahoda et al. (2023) conducted a cross-sectional in Polycystic ovary syndrome and metabolic syndrome (n=122). Polycystic ovary syndrome and metabolic syndrome vs. Metabolic syndrome alone was evaluated on Body mass index (BMI) (p=<0.05). Among obese women, the presence of both polycystic ovary syndrome and metabolic syndrome was associated with a significantly higher body mass index (33.56 vs 31.97 kg/m2) compared to metabolic syndrome alone.
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