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Vinculin's null effect on actin dynamics distinguishes it from talin; leaves open protein-specific cytoskeletal targeting in cardiovascular cell mechanics.
Analyses of dynamic light scattering data by stretched exponential fit show that vinculin has a negligible influence on internal actin filament dynamics and actin bending stiffness which contrasts with our previous observations with talin, another actin and vinculin-binding protein from focal adhesions. The results here agree with kinetic and rheologic measurements.
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Götter et al. (1995) studied this question.
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