Why the study?
Do geometric indexes of heart rate variability identify autonomic alterations in young patients with type 1 diabetes mellitus compared to healthy controls?
Do geometric indexes of heart rate variability identify autonomic alterations in young patients with type 1 diabetes mellitus compared to healthy controls?
Young patients with type 1 diabetes mellitus exhibit reduced heart rate variability compared to healthy controls, indicating early autonomic alterations.
May indicate early autonomic neuropathy in young T1DM; hypothesis-generating for geometric HRV indices in risk stratification.
To compare autonomic modulation in young patients with type 1 diabetes mellitus (DM1) (n=20) and healthy control subjects (n=23) using geometric indexes of heart rate variability (HRV) associated with linear domains of time and frequency; and to verify correlations between geometric indexes and those obtained by the time and the frequency domain of diabetic individuals. MethOdS: Heart rate was recorded as beat-to-beat with subjects supine for 30 min. The following indexes were calculated: RRtri, TINN, Poincar plot, SD1, SD2, SD1/SD2, RMSSD, SDNN, LF and HF (ms/un) and LF/HF. Visual analysis of the Poincar plot was also performed. Independent Student's t test or Mann-Whitney test, and Spearman's correlation test or Pearson's correlation test were used for statistical analysis . ReSultS: Significantly lower values of SD1, SD2, RRtri, RMSSD, SDNN, and LF and HF in ms were observed in patients with DM1 compared with healthy subjects. CONCluSiON: The Poincar plot showed less dispersion of RR intervals for the DM1 group. Strong correlations were observed with the geometric indexes with the time domain and frequency indexes.
No takes yet. Share an insight, caveat, or question.
Souza et al. (2016) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: