Why the study?
Most MDD is managed in primary care, but most real-life studies only include secondary care data, leaving the total clinical and societal burden of incident MDD across all healthcare levels uncharacterized.
Does incident major depressive disorder increase morbidity, healthcare resource utilization, work loss, and mortality compared to matched controls?
Population
137,822 patients with first unipolar MDD episode in Region Stockholm and matched controls
Comparison
Incident MDD vs matched study population controls
Design
Population-wide observational study
Authors
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May warrant integrated MDD care; leaves open whether interventions reduce excess mortality and costs.
Does incident major depressive disorder increase morbidity, healthcare resource utilization, work loss, and mortality compared to matched controls?
Incident major depressive disorder is associated with significantly increased mortality, morbidity, healthcare resource utilization, and work loss compared to the general population.
Lundberg et al. (2022) studied this question.
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