Determinants of Achieving Early Blood Pressure Control with Monotherapy in a Primary Care Setting
Population
2,185 hypertensive individuals managed in a primary care setting, mean age 59±12 years, 60% men.
Design
RCT
Follow-up
14 to 28 days
Authors
Discussion
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Member takes
Implication
Supports short-term valsartan monotherapy before escalation; extends sex-specific early-response predictors for trial stratification.
Structured PICO
P
Population
2,185 hypertensive individuals managed in a primary care setting, mean age 59±12 years, 60% men.
I
Intervention
Valsartan 80 mg/d monotherapy for 14 to 28 days.
O
Outcome
Achievement of individual blood pressure target during the run-in phase.surrogate
An initial 14-28 day period of valsartan monotherapy achieves blood pressure control in nearly 20% of hypertensive patients, particularly in women and previously untreated individuals.
Cite This Study
Stewart et al. (2013) studied this question.