Population
89 patients with chronic hepatitis C virus infection, including 50 chronic hepatitis cases, 18 liver…
Design
Cohort
Authors
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Splenomegaly and elevated vWF may associate with thrombocytopenia in chronic HCV; hypothesis-generating for endothelial dysfunction, should not yet change practice.
Vascular endothelial dysfunction, indicated by elevated vWF and soluble thrombomodulin, is involved in thrombocytopenia during chronic HCV infection alongside splenomegaly.
Osada et al. (2012) studied this question.
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