What question did this study set out to answer?

To review the clinical characteristics, hemodynamic catheterization data, and surgical outcomes in patients presenting with post-myocardial infarction ventricular septal defect.

February 1, 1969Annals of Internal Medicine

Ventricular Septal Defect After Myocardial Infarction

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Why the study?

What are the clinical findings and operative results of corrective surgery for ventricular septal defect after myocardial infarction?

Population

27 patients with ventricular septal defect after myocardial infarction

Design

Case_series

Authors

BCBrian C. CampionUniversity of Minnesota

Discussion

Member takes

Implication

May support delayed surgical closure for post-MI VSD; leaves open prospective validation of optimal timing.

Key Points

To review the clinical characteristics, hemodynamic catheterization data, and surgical outcomes in patients presenting with post-myocardial infarction ventricular septal defect.
Analyzed clinical, catheterization, and operative data from 7 patients presenting with post-infarction ventricular septal defect at the Mayo Clinic, with 6 undergoing surgical intervention.
Reviewed and integrated findings from 20 additional surgical cases identified in the published literature.
Corrective surgery was identified as the definitive treatment of choice for post-infarction ventricular septal defect.
Preoperative right heart catheterization carried a low complication risk despite the critically ill status of all evaluated patients.
Operative success improved when defect closure was postponed for at least 2 months following infarction to permit firm, fibrous healing of surrounding myocardium.

Structured PICO

What are the clinical findings and operative results of corrective surgery for ventricular septal defect after myocardial infarction?

Population

27 patients with ventricular septal defect (VSD) after myocardial infarction (7 from Mayo Clinic, 20 from literature)

Intervention

Corrective surgery (closure of VSD) and preoperative right heart catheterization

Outcome

Clinical findings, catheterization data, and operative results

Corrective surgery for post-MI VSD is recommended, ideally delayed by 2 months or more to allow for tissue healing, with preoperative right heart catheterization being safe.

Cite This Study

Brian C. Campion (1969) studied this question.

synapsesocial.com/papers/6a8bceb0effeb02058b1ebd6 https://doi.org/10.7326/0003-4819-70-2-251

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Ventricular Septal Defect After Myocardial Infarction

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Ventricular Septal Defect After Myocardial Infarction

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider