What question did this study set out to answer?

To evaluate the microbiology and antibiotic susceptibility profiles of middle ear pathogens isolated from children presenting with acute, recurrent, and treatment-failure otitis media.

December 1, 2003The Pediatric Infectious Disease Journal

Microbiology of otitis media in Costa Rican children, 1999 through 2001

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Authors

AAAdriano ArguedasPfizer (United States)RDRon DaganBen-Gurion University of the Negev CSCarolina SoleyUniversidad de Ciencias Medicas

Discussion

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Implication

Surveillance study reveals pathogen distributions and penicillin nonsusceptibility in pediatric otitis media, highlighting the need for targeted therapies.

Key Points

To evaluate the microbiology and antibiotic susceptibility profiles of middle ear pathogens isolated from children presenting with acute, recurrent, and treatment-failure otitis media.
Conducted surveillance in Costa Rica between 1999 and 2001 by collecting middle ear fluid from 276 pediatric patients categorized into acute otitis media (N=102), recurrent otitis media (N=98), and treatment failure (N=76).
Isolated bacterial pathogens, evaluated antibiotic susceptibility and beta-lactamase activity, and performed serotyping and pulsed-field gel electrophoresis on available Streptococcus pneumoniae isolates.
Streptococcus pneumoniae was the most prevalent pathogen overall (88 strains), whereas Haemophilus influenzae was significantly more prevalent in treatment-failure cases (P=0.015).
Penicillin-nonsusceptible Streptococcus pneumoniae occurred at significantly higher rates in treatment-failure (64%) and recurrent cases (63%) compared to acute otitis media cases (42%, P=0.05), with serotype 19F predominating.
Beta-lactamase activity was detected in 7% (3/41) of Haemophilus influenzae isolates and 100% (3/3) of Moraxella catarrhalis isolates, with Streptococcus pyogenes identified in 10 cases.

Cite This Study

Arguedas et al. (2003) studied this question.

synapsesocial.com/papers/6a8bd04ceffeb02058b1ec15 https://doi.org/10.1097/01.inf.0000101189.81501.e9

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Implication

Surveillance study reveals pathogen distributions and penicillin nonsusceptibility in pediatric otitis media, highlighting the need for targeted therapies.

Microbiology of otitis media in Costa Rican children, 1999 through 2001

Discussion

Member takes

Implication

Key Points

Cite This Study

Microbiology of otitis media in Costa Rican children, 1999 through 2001

Discussion

Member takes

Implication

Key Points

Cite This Study

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