What question did this study set out to answer?

To characterize the clinical presentation, epidemiology, and antimicrobial resistance profiles of Streptococcus pneumoniae serotype 3 in pediatric middle ear infections.

August 14, 2009BMC PediatricsOpen Access

Streptococcus pneumoniaeSerotype 3 among Costa Rican Children with Otitis Media: clinical, epidemiological characteristics and antimicrobial resistance patterns

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Authors

AAArturo AbdelnourPrisma Health CSCarolina SoleyUniversidad de Ciencias Medicas SGSilvia GuevaraUniversidad de Ciencias Medicas

Discussion

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Implication

Surveillance study reveals low penicillin resistance in Streptococcus pneumoniae serotype 3 among children with otitis media, suggesting preserved drug susceptibility in older toddlers.

Key Points

To characterize the clinical presentation, epidemiology, and antimicrobial resistance profiles of Streptococcus pneumoniae serotype 3 in pediatric middle ear infections.
Analyzed middle ear fluid obtained from 1,919 tympanocentesis procedures performed in Costa Rican children (median age: 19 months) during antimicrobial clinical trials between 1992 and 2007.
Identified bacterial pathogens and serotyped 346 S. pneumoniae isolates recovered between 1999 and 2006, assessing susceptibility to penicillin and other antibiotics using E-tests.
S. pneumoniae was the most prevalent pathogen (511/1,208 isolates; 49%), with serotype 3 representing the third most frequent serotype (34/346; 10.1%), behind 19F (30.0%) and 14 (13.7%).
Serotype 3 isolates were significantly more frequent in children older than 24 months compared to other serotypes (61.2% vs 40.6%; P = 0.05).
Penicillin non-susceptibility was significantly lower in serotype 3 isolates than in non-serotype 3 isolates (4.0% vs 18%; P = 0.003).

Cite This Study

Abdelnour et al. (2009) studied this question.

synapsesocial.com/papers/6a9069f3fdaee66aea840cc7 https://doi.org/10.1186/1471-2431-9-52

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Implication

Surveillance study reveals low penicillin resistance in Streptococcus pneumoniae serotype 3 among children with otitis media, suggesting preserved drug susceptibility in older toddlers.

Streptococcus pneumoniaeSerotype 3 among Costa Rican Children with Otitis Media: clinical, epidemiological characteristics and antimicrobial resistance patterns

Discussion

Member takes

Implication

Key Points

Cite This Study

Streptococcus pneumoniaeSerotype 3 among Costa Rican Children with Otitis Media: clinical, epidemiological characteristics and antimicrobial resistance patterns

Discussion

Member takes

Implication

Key Points

Cite This Study

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