Why the study?
What are the risk factors for an abnormal echocardiogram in childhood cancer survivors treated with anthracyclines and/or radiation?
Population
370 childhood cancer survivors with a history of anthracyclines and/or radiation seen in a long-term…
Design
Cohort
Authors
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Supports risk-adapted surveillance in survivors; extends prior associations but remains hypothesis-generating.
What are the risk factors for an abnormal echocardiogram in childhood cancer survivors treated with anthracyclines and/or radiation?
In childhood cancer survivors, an anthracycline dose ≥250 mg/m2 and underweight status are associated with an increased risk of late cardiac toxicity as detected by abnormal echocardiograms.
Andolina et al. (2010) studied this question.
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