Population
Embryonic fibroblasts and cardiac myocytes from tissue-specific cell cycle indicator BAC transgenic mouse…
Design
Preclinical
Authors
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Challenges earlier reports of a P15 cardiomyocyte proliferation burst; hypothesis-generating for RV-LV differences in perinatal myocyte cell cycle activity.
A novel cardiac myocyte-specific cell cycle reporter reveals reduced cell cycle activity in right versus left ventricular myocytes perinatally and refutes a previously reported burst of activity at postnatal day 15.
Hirai et al. (2015) studied this question.