Specific MRI features such as blood-filled cystic spaces with fluid-fluid levels and an enhancing fibrous pseudocapsule can help differentiate angiomatoid fibrous histiocytoma from other soft tissue tumors.
OBJECTIVE: Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue tumor usually affecting the extremities of children and young adults and has a favorable prognosis. The purpose of this study was to report the magnetic resonance imaging appearance in 2 cases of AFH. CONCLUSIONS: Although the overall features of AFH can be confused with other subtypes of malignant fibrous histiocytoma, the young age at presentation, the location of the mass, the presence of intralesional blood-filled cystic spaces with fluid-fluid levels, associated features of hemosiderin deposition, and an enhancing fibrous pseudocapsule are all potential hints favoring this entity.
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Ajlan et al. (2010) studied this question.
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