Why the study?
Does digitalis improve ventricular rate and circulatory failure in ambulatory patients with auricular fibrillation and moderate congestive heart failure?
Population
Ambulatory patients with auricular fibrillation and moderate congestive heart failure
Design
Cohort
Follow-up
many weeks
Authors
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May guide initial digitalis dosing in ambulatory AF with HF; leaves open optimal long-term regimens pending randomized data.
Does digitalis improve ventricular rate and circulatory failure in ambulatory patients with auricular fibrillation and moderate congestive heart failure?
A fixed daily dose of digitalis produces progressive slowing of ventricular rate initially, followed by a constant rate, suggesting incomplete initial excretion.
H Otto (1933) studied this question.
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