Why the study?
Does echocardiographic strain/strain rate imaging and twist improve the evaluation of systolic function and prognosis in patients with aortic stenosis?
Does echocardiographic strain/strain rate imaging and twist improve the evaluation of systolic function and prognosis in patients with aortic stenosis?
Echocardiographic strain and twist imaging offer sensitive, emerging parameters for evaluating left ventricular function and prognosis in aortic stenosis, overcoming limitations of traditional ejection fraction.
Systolic function of the left ventricle is vital for patients with aortic stenosis. Unfortunately, the most widely used clinical parameter, the left ventricular ejection fraction, is not sensitive enough, especially for patients with left ventricular hypertrophy. Echocardiographic strain/strain rate and twist are emerging parameters for left ventricular systolic and diastolic function evaluation. Aortic stenosis could reduce strain/strain rate while magnifying twist. Furthermore, strain/strain rate correlates well with the prognosis of patients with aortic stenosis. Most importantly the circumferential strain, strain rate and twist also play a role in differentiating cardiac compensation or decompensation. In any case, these parameters could normalize after successful surgical aortic valve replacement or transcatheter aortic valve replacement. Regardless of these advantages, clinical evidence is needed to ensure their usefulness.
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Wang et al. (2013) studied this question.
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