Why the study?
Does diabetic acidosis alter the pattern of C-14 incorporation into fatty acids in platelets compared to normal subjects?
Population
Platelets from normal subjects and patients in diabetic acidosis
Comparison
Diabetic acidosis vs Normal subjects
Design
Case-control
Authors
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Diabetic acidosis may alter platelet fatty acid profiling; hypothesis-generating and should not yet change practice or guide research priorities.
Does diabetic acidosis alter the pattern of C-14 incorporation into fatty acids in platelets compared to normal subjects?
Diabetic acidosis significantly alters the qualitative and quantitative pattern of fatty acid synthesis in platelets, suppressing the cytoplasmic pathway while potentially stimulating the mitochondrial pathway.
Awai et al. (1964) studied this question.
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