Why the study?
Up to 15% of Ross patients experience autograft failure, and the underlying mechanisms of failure remain incompletely understood.
Does four-dimensional flow magnetic resonance imaging demonstrate normalization of aortic flow after the Ross procedure?
Does four-dimensional flow magnetic resonance imaging demonstrate normalization of aortic flow after the Ross procedure?
4D flow MRI can demonstrate near normalization of aortic flow following the Ross procedure, providing insights into postoperative hemodynamics.
4D flow MRI findings after Ross are hypothesis-generating; larger prospective studies needed to link flow normalization to outcomes.
The Ross procedure was first described in 1967. In it, the diseased aortic valve is replaced with a pulmonary autograft and the pulmonary valve is replaced with a homograft.1 Benefits of the Ross procedure include improved survival in patients younger than age 50 years, superior hemodynamics compared with manmade prostheses, and avoidance of lifetime anticoagulation therapy.2 This procedure is experiencing a resurgence largely due to the demonstration of a survival benefit. Contemporary series have shown operative mortality on par with aortic valve replacement; however, up to 15% of Ross patients still experience autograft failure and the mechanisms of failure are incompletely understood.
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Stellon et al. (2024) studied this question.
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