Why the study?
Does intradermal administration of fractional doses of inactivated poliovirus vaccine provide adequate immunogenicity and operational feasibility compared to full intramuscular doses?
Population
General population targeted for polio immunization
Comparison
Fractional dose of inactivated poliovirus… vs Full vaccine dose administered by the…
Design
Review
Authors
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Supports fractional dosing as a viable strategy to stretch global vaccine supply; leaves open the need for long-.
Does intradermal administration of fractional doses of inactivated poliovirus vaccine provide adequate immunogenicity and operational feasibility compared to full intramuscular doses?
Intradermal administration of fractional doses of inactivated poliovirus vaccine is an immunogenic and operationally feasible dose-sparing strategy to stretch global vaccine supply.
Okayasu et al. (2017) studied this question.
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