Why the study?
Does spontaneous ventilation alter myocardial perfusion compared to mechanical ventilation in ventilator-dependent patients?
Population
15 ventilator-dependent patients who cannot be separated from mechanical ventilation after an episode of…
Comparison
Spontaneous ventilation through a T-piece for at… vs Intermittent mechanical ventilation (IMV).
Design
Cohort
Authors
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May implicate ischemia in weaning failure; hypothesis-generating observation requiring prospective confirmation before practice change.
Does spontaneous ventilation alter myocardial perfusion compared to mechanical ventilation in ventilator-dependent patients?
Spontaneous ventilation in ventilator-dependent patients can induce myocardial perfusion abnormalities and transient LV dilation, suggesting ischemia may contribute to weaning failure.
Hurford et al. (1991) studied this question.
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