Key result
Thallium-201 infusion MPSPECT after oral glucose application yielded higher segmental perfusion improvement (27.2%) compared to redistribution (16.3%) and 24-hour late MPSPECT (18.3%) images.
Why the study?
Does thallium-201 infusion MPSPECT after oral glucose application improve the detection of myocardial viability compared to standard rest/redistribution/24h-late imaging in nondiabetic patients with chronic coronary artery disease?
Population
33 nondiabetic patients with history of myocardial infarction or known chronic coronary artery disease.
Comparison
Thallium-201 infusion myocardial perfusion… vs Rest/redistribution and 24 h-late-MPSPECT…
Design
Cross-sectional
Authors
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May support glucose-augmented thallium MPSPECT for viability assessment in chronic CAD; hypothesis-generating and should not yet change practice.
Cross-Sectional (n=33)
Does thallium-201 infusion MPSPECT after oral glucose application improve the detection of myocardial viability compared to standard rest/redistribution/24h-late imaging in nondiabetic patients with chronic coronary artery disease?
Absolute Event Rate: 27.2% vs 18.3%
Thallium-201 infusion MPSPECT after oral glucose application improves the detection of myocardial viability in nondiabetic patients with chronic coronary artery disease compared to standard imaging protocols.
Hasbek et al. (2009) conducted a cross-sectional in chronic coronary artery disease or past myocardial infarction (n=33). Thallium-201 infusion MPSPECT after oral glucose application vs. Redistribution and 24 h-late-MPSPECT imaging was evaluated on Segmental perfusion improvement. Thallium-201 infusion MPSPECT after oral glucose application yielded higher segmental perfusion improvement (27.2%) compared to redistribution (16.3%) and 24-hour late MPSPECT (18.3%) images.
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