Synthesis of Nucleosides Fluorinated in the Sugar Moiety. The Application of Diethylaminosulfur Trifluoride to the Synthesis of Fluorinated Nucleosides

A survey is given of the different methods that have been used for the synthesis of nucleosides fluorinated in the carbohydrate moiety. In this article we describe the use of diethylaminosulfur trifluoride (DAST) as a fluorinating agent in the nucleoside field.