The Breastfeeding Period: A Critical Opportunity to Expand Access to Hepatitis C Cure

Q: What does this research mean for the field?

The breastfeeding period represents a critical opportunity to expand access to Hepatitis C cure, and emerging pharmacokinetic data on glecaprevir-pibrentasvir in breast milk provides essential groundwork for future safety studies. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.ESTABLISHES_NEW_DIRECTION.

Audrey R. Lloyd

doi:10.1093/cid/ciag505

August 21, 2026Clinical Infectious Diseases

The Breastfeeding Period: A Critical Opportunity to Expand Access to Hepatitis C Cure

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Key Points

To examine the pharmacokinetics of glecaprevir-pibrentasvir in breast milk to support safe treatment options for women with hepatitis C during lactation.
Reviewed pharmacokinetic data analyzing drug concentrations of glecaprevir-pibrentasvir (GLE/PIB) in human breast milk.
Pharmacokinetic profiling characterized the excretion of glecaprevir-pibrentasvir into breast milk.
The findings establish critical preliminary evidence to guide future clinical safety studies and reduce treatment delays for postpartum patients.

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Implication

Pharmacokinetic analysis demonstrates glecaprevir-pibrentasvir levels in breast milk among lactating women, indicating pathways to expand hepatitis C cure access.

Abstract

Women living with hepatitis C (HCV) must often choose between breastfeeding or accessing HCV cure. The analysis reported by McCrary et al. on the pharmacokinetics of glecaprevir-pibrentasvir (GLE/PIB) in breast milk lays important groundwork to support future studies informing safety.

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Cite This Study

Audrey R. Lloyd (2026) studied this question.

synapsesocial.com/papers/6a8c00b3bca056c88e6df865 https://doi.org/10.1093/cid/ciag505

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The Breastfeeding Period: A Critical Opportunity to Expand Access to Hepatitis C Cure

Key Points

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Implication

Abstract

Discussion

Cite This Study

The Breastfeeding Period: A Critical Opportunity to Expand Access to Hepatitis C Cure

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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