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August 24, 2026Diseases of the Esophagus

P1.013. Outcomes of Heller-Dor Myotomy and Per-Oral Endoscopic Myotomy for Esophageal Achalasia

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Authors

KKKengo KuriyamaGunma UniversityMSMakoto SakaiGunma UniversityKUKosei UeharaGunma University

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Overview

Retrospective review reveals comparable symptom relief between Heller-Dor and per-oral endoscopic myotomy for achalasia, indicating higher reflux rates after endoscopy.

Key Points

  • To evaluate the surgical techniques and clinical outcomes of Heller myotomy with Dor fundoplication versus per-oral endoscopic myotomy in patients with esophageal achalasia.
  • Retrospective review of 68 patients with esophageal achalasia treated at a single institution (54 undergoing Heller-Dor [HD] and 14 undergoing per-oral endoscopic myotomy [POEM]).
  • HD involved a 6-cm esophageal and 2-cm gastric myotomy with Dor fundoplication (mostly laparoscopic, n=51), while POEM utilized circular muscle myotomy through a submucosal tunnel.
  • Outcomes measured included Eckardt score, lower esophageal sphincter pressure (LESP), and postoperative reflux esophagitis via Los Angeles classification.
  • Eckardt scores improved significantly in both the HD group (from 5.6 to 1.4, p < 0.001) and the POEM group (from 5.9 to 1.4, p < 0.001).
  • Lower esophageal sphincter pressure decreased significantly in both cohorts: HD (from 22.6 to 16.3 mmHg, p = 0.017) and POEM (from 31.2 to 12.3 mmHg, p = 0.002).
  • Postoperative reflux esophagitis (Grade A or higher) occurred more frequently after POEM (37.5%) compared to HD (9.3%, p = 0.029), though all cases were medically managed.

Cite This Study

Kuriyama et al. (2026) studied this question.

synapsesocial.com/papers/6a8c00d0bca056c88e6dfd79https://doi.org/10.1093/dote/doag077.161
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Peroral Endoscopic Myotomy Versus Laparoscopic Heller Myotomy for Achalasia: A Meta-Analysis of Randomized Controlled Trials2025
  2. 2The Evolving Role of Heller-Dor in the Poem Era2025
  3. 3Achalasia: laparoscopic Heller myotomy with fundoplication versus peroral endoscopic myotomy—a systematic review and meta-analysis2024 · 22 citations
  4. 4Laparoscopic Heller–Dor as salvage therapy after failed POEM: a prospective comparative study2026
  5. 5254. THE CHANGES OF HIGH RESOLUTION ESOPHAGEAL MANOMETRY AFTER PERORAL ENDOSCOPIC MYOTOMY2025