What question did this study set out to answer?

To determine the prevalence of encephalomyocarditis virus neutralizing and hemagglutination inhibition antibodies across rural human populations.

November 1, 1963Experimental Biology and Medicine

Demonstration of Encephalomyocarditis Virus Antibody in Human Serums From Panama

View Full Paper

Ask AI

Bookmark

Population

180 human sera collected in 4 geographically separated, rural areas of the Republic of Panama

Design

Cross-sectional

Authors

JCJohn E. CraigheadUniversity of Vermont PPPauline H. PeraltaInstituto Conmemorativo Gorgas de Estudios de la Salud ASAlexis ShelokovUniversidad de Panamá

Discussion

Member takes

Implication

May indicate EMCV circulation in rural Panama; leaves open zoonotic risks and pediatric patterns for prospective confirmation.

Key Points

To determine the prevalence of encephalomyocarditis virus neutralizing and hemagglutination inhibition antibodies across rural human populations.
Tested 180 human serum samples collected from four geographically separated rural areas.
Screened all sera for encephalomyocarditis virus neutralizing antibodies and tested positive specimens for hemagglutination inhibition antibody.
Encephalomyocarditis virus neutralizing antibody was present in 36 of 180 human sera (20%), with prevalence exceeding 15% across all four individual areas.
Hemagglutination inhibition antibody was detected in 58% of the sera that tested positive for neutralizing antibodies.
Children demonstrated a significantly higher incidence of neutralizing antibody than adults.

Structured PICO

Population

180 human sera collected in 4 geographically separated, rural areas of the Republic of Panama

Outcome

Presence of Encephalomyocarditis (EMC) virus neutralizing antibodysurrogate

This study demonstrates a 20% seroprevalence of Encephalomyocarditis virus neutralizing antibodies in rural Panama, with higher rates observed in children.

Cite This Study

Craighead et al. (1963) studied this question.

synapsesocial.com/papers/6a8c05ddeada60f85de3d50f https://doi.org/10.3181/00379727-114-28714

Topics

Sermorelin

View Full Paper

Ask AI

Bookmark

Demonstration of Encephalomyocarditis Virus Antibody in Human Serums From Panama

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Demonstration of Encephalomyocarditis Virus Antibody in Human Serums From Panama

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider