Key result
Stroke-prone spontaneously hypertensive rats had significantly higher peak Ca2+ current amplitudes than normotensive rats (446 vs 156 pA).
Absolute Event Rate: 446% vs 156%
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Does not inform clinical hypertension management; leaves open Ca2+ current role in human vascular pathology.
Self et al. (2008) studied Hypertension. Stroke-prone spontaneously hypertensive rat (SP-SHR) strain vs. N/nih outbred normotensive rats was evaluated on Peak current amplitudes in 20 mM Ba2+. Stroke-prone spontaneously hypertensive rats had significantly higher peak Ca2+ current amplitudes than normotensive rats (446 vs 156 pA).
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