Population
Single cells freshly isolated from resistance mesenteric arteries from 4- to 5-week-old and 16- to…
Comparison
Whole-cell voltage clamp measurement vs Wistar-Kyoto (WKY) rats (normotensive controls)
Design
Preclinical
Authors
Loading...
Hypothesis-generating for L-type Ca2+ channel upregulation in early hypertension; leaves open relevance to human disease.
Increased activity of voltage-dependent L-type Ca2+ channels in resistance arteries of young spontaneously hypertensive rats may be related to the development of hypertension.
Ohya et al. (1993) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: