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May 1, 1993AJP Heart and Circulatory Physiology

Enhanced single-channel K+ current in arterial membranes from genetically hypertensive rats

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Authors

SESarah K. EnglandWashington University in St. Louis TWTheresa A. WooldridgeSemiconductor Research Corporation WSWilliam J. StekielMedical College of Wisconsin

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Implication

Enhanced IK(Ca) in SHR arteries may buffer tone; leaves open human relevance and therapeutic targeting.

Key Points

Key points are not available for this paper at this time.

Cite This Study

England et al. (1993) studied this question.

synapsesocial.com/papers/6a73ea9e0f8808cba78ded3d https://doi.org/10.1152/ajpheart.1993.264.5.h1337

Topics

Hypertension management

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Increased Expression of Ca 2+ -Sensitive K + Channels in Aorta of Hypertensive Rats1997 · 128 citations
2Calcium exerts a larger regulatory effect on potassium+ channels in small mesenteric artery mycoytes from spontaneously hypertensive rats compared to Wistar-Kyoto rats2003 · 17 citations
3Ca2+-Sensitive K+ Channel in Aortic Smooth Muscle of Rats1991 · 10 citations
4Comparison of K+ channel properties in freshly isolated myocytes from thoracic aorta of WKY and SHR1996 · 37 citations
5Alterations in Rat Interlobar Artery Membrane Potential and K+Channels in Genetic and Nongenetic Hypertension1996 · 129 citations