Population
Isolated thoracic aorta myocytes from 13 to 15 week old Wistar-Kyoto and spontaneously hypertensive rats
Comparison
Whole cell voltage clamp methods to record K+… vs Wistar-Kyoto normotensive rats compared to…
Design
Preclinical
Authors
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Reduced Kv currents in SHR aortic myocytes may reflect vascular remodeling in hypertension; hypothesis-generating and leaves open human relevance.
Voltage-gated potassium (Kv) currents are smaller in thoracic aorta myocytes of spontaneously hypertensive rats compared to normotensive controls, suggesting altered resting K+ conductance in hypertension.
R. H. Cox (1996) studied this question.
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