Highlights a cluster of liver angiosarcoma cases in a rural population without known occupational exposure to PVC.
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Alerts clinicians to non-PVC etiologies in hepatic angiosarcoma; hypothesis-generating for rural environmental risks requiring investigation.
Angiosarcoma of the liver has recently been publicized because of its association with polyvinyl chloride (PVC) polymerization workers. Four cases of this rare tumor have been observed at the Marshfield Clinic within a 29-month period. There are no factories that manufacture PVC products in the immediate area, nor were any of the victims ever involved in such manufacturing work. Thus, it is possible that other factors may be related to this cluster of the disease.
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Justus J. Fiechtner (1976) studied this question.
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