Key result
Carotid baroreceptor electric stimulation and renal denervation are emerging therapeutic options for resistant hypertension currently under evaluation in ongoing clinical trials.
Carotid baroreceptor electric stimulation and renal denervation are emerging as new therapeutic approaches for resistant hypertension, with ongoing trials evaluating their long-term efficacy and safety.
Resistant hypertension, namely the hypertensive state characterized by the inability of multiple antihypertensive drug interventions to lower blood pressure to goal levels, represents a condition frequently detected in clinical practice. Its main features are represented by its heterogeneous etiology as well as its very high cardiovascular risk. This latter peculiarity has implemented the research for new approaches to the treatment of the disease. This article will focus on two of them, namely carotid baroreceptor electric stimulation and the renal denervation procedure. Clinical studies and large-scale clinical trials are presently ongoing with the aim of defining the long-term efficacy and safety profile of the two interventions.
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Grassı et al. (2010) conducted a review in Resistant hypertension. Carotid baroreceptor electric stimulation and renal denervation was evaluated. Carotid baroreceptor electric stimulation and renal denervation are emerging therapeutic options for resistant hypertension currently under evaluation in ongoing clinical trials.
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