Key result
Younger patients (<40 years) with coronary heart disease had a significantly higher prevalence of smoking (70% vs 46%) and family history of IHD, but lower rates of hypertension and diabetes compared to older patients.
Population
100 patients with clinically diagnosed Coronary Heart Disease undergoing coronary angiographic evaluation.
Design
Cohort
Authors
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Supports smoking cessation focus in young adults; leaves open whether age-specific profiles warrant tailored prevention trials.
Observational (n=100)
No
Absolute Event Rate: 70% vs 46%
p-value: p=0.032
Premature coronary artery disease in young adults is strongly associated with preventable risk factors like smoking and family history, but presents with less extensive angiographic disease compared to older patients.
Siddique et al. (2010) conducted an observational in Coronary Heart Disease (n=100). Young age (<40 years) vs. Older age (>40 years) was evaluated on Smoking prevalence (p=0.032). Younger patients (<40 years) with coronary heart disease had a significantly higher prevalence of smoking (70% vs 46%) and family history of IHD, but lower rates of hypertension and diabetes compared to older patients.
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