Why the study?
A guideline was needed to update and harmonize exercise-based cardiac rehabilitation indications, contents, and delivery in German-speaking European countries.
Does exercise-based cardiac rehabilitation improve clinical outcomes, exercise capacity, and quality of life in patients with cardiovascular diseases?
Meta-Analysis
Does exercise-based cardiac rehabilitation improve clinical outcomes, exercise capacity, and quality of life in patients with cardiovascular diseases?
This guideline reinforces the substantial benefit of exercise-based cardiac rehabilitation across specific cardiac indications and highlights the importance of treatment intensity and individualized care.
Supports routine referral to exercise-based cardiac rehabilitation post-ACS/CABG and in HFrEF; confirms mortality and functional benefits in updated Level 1 synthesis.
A scientific guideline has been developed to update and harmonize exercise based cardiac rehabilitation (CR) in German speaking countries of Europe. It addresses all aspects of CR including indications, contents and delivery. Four meta-analyses were performed to evaluate the prognostic effect of CR after acute coronary syndrome (ACS), after coronary bypass grafting (CABG), in patients with systolic heart failure (HFrEF), and to define the effect of psychological interventions during CR. Other indications for CR were based on a predefined semi-structured literature search and recommendations were established by a formal consenting process. CR is associated with a significant reduction in all-cause mortality in patients after ACS and CABG, whereas HFrEF-patients benefit in terms of exercise capacity and health-related quality of life. Patients with other cardiovascular diseases such as heart valve surgery or intervention, adults with congenital heart disease and peripheral arterial disease also benefit from CR-participation, but the scientific evidence is less clear. There is increasing evidence that the beneficial effect of CR strongly depends on "treatment intensity" including medical supervision, modulation of cardiovascular risk factors, information and education, and a minimum of individually adapted exercise volume. Additional psychologic interventions (PI) should be performed on the basis of individual needs. There was a trend towards reduction of depressive symptoms for "distress management" and "lifestyle changes" for PI. Patient education is able to increase patients` knowledge and motivation as well as behavior changes regarding physical activity, dietary habits and smoking cessation. Diversity-sensitive structures should be established to interact with the needs of special patient groups and gender issues. This guideline reinforces the substantial benefit of CR in specific cardiac indications, and it points out the minimal therapeutic needs in CR-delivery.
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Bernhard Schwaab (2022) conducted a meta-analysis in Cardiovascular diseases (ACS, CABG, HFrEF). Exercise-based cardiac rehabilitation was evaluated on All-cause mortality, exercise capacity, and health-related quality of life. Exercise-based cardiac rehabilitation significantly reduced all-cause mortality in patients after ACS and CABG, and improved exercise capacity and quality of life in patients with HFrEF.
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