Why the study?
Coronary heart disease is the most common reason for referral to exercise-based cardiac rehabilitation globally, but the generalizability of previous meta-analyses of randomized controlled trials has been questioned.
Does exercise-based cardiac rehabilitation reduce mortality and recurrent clinical events, and improve health-related quality of life in adults with coronary heart disease?
Population
23 430 adults with MI, angina pectoris, or after CABG or PCI from 85 RCTs
Comparison
Exercise-based cardiac rehabilitation vs no-exercise control
Design
Systematic review and random-effects meta-analysis of RCTs
Follow-up
Median 12-month
Key result
Exercise-based cardiac rehabilitation reduced cardiovascular mortality by 26% and hospitalizations by 23% in patients with coronary heart disease (RR: 0.74, RR: 0.77).
Authors
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Supports routine referral to exercise-based cardiac rehabilitation in coronary heart disease; confirms benefits across updated randomized trials.
Does exercise-based cardiac rehabilitation reduce mortality and recurrent clinical events, and improve health-related quality of life in adults with coronary heart disease?
Exercise-based cardiac rehabilitation significantly reduces cardiovascular mortality, hospitalizations, and recurrent myocardial infarction in patients with coronary heart disease.
Dibben et al. (2023) studied this question. Exercise-based cardiac rehabilitation reduced cardiovascular mortality by 26% and hospitalizations by 23% in patients with coronary heart disease (RR: 0.74, RR: 0.77).
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