Key result
Exercise-based cardiac rehabilitation significantly reduced mortality in patients with acute coronary syndrome compared to no rehabilitation (HR -0.47; 95% CI -0.56 to -0.39; P<0.05).
Why the study?
To detect the impact of cardiac rehabilitation on mortality and major adverse cardiac events in patients with acute coronary syndrome.
Does exercise-based cardiac rehabilitation reduce mortality and major adverse cardiac events in patients with acute coronary syndrome?
Population
55 035 participants with ACS across 25 studies
Comparison
Cardiac rehabilitation vs non-CR control
Design
Meta-analysis
Authors
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Supports routine exercise-based cardiac rehabilitation after ACS; confirms mortality benefit in meta-analysis of 55,035 patients.
Meta-Analysis (n=55,035)
Does exercise-based cardiac rehabilitation reduce mortality and major adverse cardiac events in patients with acute coronary syndrome?
Hazard Ratio: -0.47 (95% CI -0.56–-0.39)
p-value: p=<0.05
Exercise-based cardiac rehabilitation is associated with significant reductions in mortality, major adverse cardiac events, MI recurrence, and the need for revascularization in patients with acute coronary syndrome.
Ji et al. (2019) conducted a meta-analysis in Acute coronary syndrome (ACS) (n=55,035). Exercise-Based Cardiac Rehabilitation vs. Non-CR group was evaluated on Mortality (HR -0.47, 95% CI -0.56 to -0.39, p=<0.05). Exercise-based cardiac rehabilitation significantly reduced mortality in patients with acute coronary syndrome compared to no rehabilitation (HR -0.47; 95% CI -0.56 to -0.39; P<0.05).
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