T wave inversion can occur as a direct result of prolonged tachycardia, mimicking coronary ischemia without underlying structural heart disease.
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Consider post-tachycardic T-wave inversion in ischemia differentials; leaves open generalizability beyond single-case reports.
For several years I have been struck by odd cases where changes in the T waves and even sharp inversion of these waves after long paroxysms of tachycardiain appearance suggestive of coronary occlusion or at least of coronary disease-seemed from the subsequent course of the patient to be no more than the effect of the long paroxysm. Sometimes when these changes were observed it was difficult to exclude active though undiagnosed myocardial disease, such as might follow a silent cardiac infarct; and sometimes the patient had taken digitalis or quinidine in an effort to arrest the attack in such amounts that these might possibly have caused the T wave inversion, though considering the dosage and the short time for which the drug was taken this seemed most unlikely.
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M. Campbell (1942) studied this question.
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