What question did this study set out to answer?

To evaluate the safety, hemodynamic efficacy, and durability of percutaneous atrial septal stent implantation for creating an unrestrictive interatrial communication in infants with obstructive left heart defects.

May 1, 2006Congenital Heart Disease

Atrial Septal Stent Implant: Atrial Septal Defect Creation in the Management of Complex Congenital Heart Defects in Infants

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Why the study?

Does percutaneous atrial septal stent implantation improve left atrial pressure and ASD diameter in infants with left heart obstructive defects who are poor surgical candidates?

Key Points

To evaluate the safety, hemodynamic efficacy, and durability of percutaneous atrial septal stent implantation for creating an unrestrictive interatrial communication in infants with obstructive left heart defects.
Reviewed 5 infants (aged 5 weeks to 17 months; weight 3.5–10.1 kg) with left heart obstructive defects, severe left atrial hypertension, and high surgical risk.
Implanted a premounted Palmaz-Genesis stent across the atrial septum using standard percutaneous technique with balloon diameters ranging from 7 to 10 mm.
Stent deployment succeeded in all 5 patients, producing an immediate, marked reduction in left atrial pressure and an increase in atrial septal defect diameter.
All created atrial communications remained widely patent on serial Doppler echocardiography until elective surgical stent removal.

Structured PICO

Does percutaneous atrial septal stent implantation improve left atrial pressure and ASD diameter in infants with left heart obstructive defects who are poor surgical candidates?

Population

n=5 infants (aged 5 weeks to 17 months, weighing 3.5-10.1 kg) with left heart obstructive defects and severe left atrial hypertension, who were poor surgical candidates.

Intervention

Percutaneous implantation of a premounted Palmaz-Genesis stent across the atrial septum using 7 to 10 mm diameter balloons.

Outcome

Decrease in left atrial pressure and increased atrial septal defect (ASD) diameter.surrogate

Percutaneous atrial septal stent implantation is an effective technique for achieving immediate hemodynamic improvement and relieving severe left atrial hypertension in infants with complex congenital heart defects who are poor surgical candidates.

Discussion

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Implication

May support stenting as bridge in select high-risk infants; hypothesis-generating and requires prospective validation before broader use.

Cite This Study

Leonard et al. (2006) studied this question.

synapsesocial.com/papers/6a8c1e8a2ff0ab4f91e96694 https://doi.org/10.1111/j.1747-0803.2006.00022.x

Topics

Hypertension management Congenital heart disease adults

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Bookmark

Atrial Septal Stent Implant: Atrial Septal Defect Creation in the Management of Complex Congenital Heart Defects in Infants

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Topics

Atrial Septal Stent Implant: Atrial Septal Defect Creation in the Management of Complex Congenital Heart Defects in Infants

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider