Key result
Apixaban use was associated with the development of biopsy-proven acute interstitial nephritis in a 70-year-old man, which resolved after drug discontinuation and steroid therapy.
Case Report (n=1)
No
Apixaban can cause acute interstitial nephritis, emphasizing the importance of monitoring renal function in patients receiving direct oral anticoagulants.
Answers are grounded in this paper and cite their sources.
Apixaban may cause acute interstitial nephritis; this case leaves open whether it is a class effect among DOACs.
Direct oral anticoagulants (DOACs)-dabigatran, rivaroxaban, apixaban and edoxaban-are changing the landscape of clinical practice for patients requiring short and long-term anticoagulation. We report a patient with no history of kidney disease developing acute interstitial nephritis (AIN) after starting a DOAC, apixaban. To date, this is the first biopsy proven case of apixaban-induced AIN.
No takes yet. Share an insight, caveat, or question.
DiMaria et al. (2019) conducted a case report in Acute interstitial nephritis (n=1). Apixaban was evaluated on Acute interstitial nephritis. Apixaban use was associated with the development of biopsy-proven acute interstitial nephritis in a 70-year-old man, which resolved after drug discontinuation and steroid therapy.
Synapse has enriched 10 related papers. Consider them for comparative context: