Vaccination Against Measles: Part III. Clinical Trial in British Children

This is the authors' abstract. We don't add key points for this paper.

The studies of measles vaccine in the United States reported by Katz et al. (1960a, 1960b) included children living in institutions.Vaccination against measles is likely to have a special application in these circum- stances, where measles may be associated with serious morbidity and a high mortality.In this investigation the clinical and antibody response to three vaccines has been studied among mentally deficient children at the Fountain Hospital, Tooting.London, and at Queen Mary's Hospital, Carshalton, Surrey.These hospitals together provide accommoda- tion for 600 severely subnormal children in the imbecile and idiot range.They were especially suitable for the study since close medical supervision was possible throughout. ProcedureIn December, 1960, samples of serum were taken from 107 children and examined for measles neutralizing