Key result
Intraoperative iatrogenic type A aortic dissection occurred in 7 of 3,000 open heart cases (0.23% incidence), with increased mortality linked to low aortic pressure, advanced age, and delayed diagnosis.
Why the study?
What are the risks, causative mechanisms, and outcomes of intraoperative iatrogenic type A aortic dissection during open heart surgery?
Observational (n=3,000)
What are the risks, causative mechanisms, and outcomes of intraoperative iatrogenic type A aortic dissection during open heart surgery?
Intraoperative iatrogenic type A aortic dissection is a rare (0.23%) but serious complication of open heart surgery, with outcomes dependent on prompt diagnosis and hemodynamic management.
Heightened vigilance for dissection in elderly patients may improve survival; leaves open prospective validation of risk factors.
We assessed the risks and causative mechanisms of intraoperative iatrogenic aortic dissection type A. During a 3-year period (2002-2004) with 3000 open heart cases, 7 patients sustained an intraoperative aortic dissection type A, resulting in an incidence of 0.23%. The original procedures were mitral valve replacement in 3 patients, aorto coronary bypass surgery in 2 patients, ascending aortic replacement with aortic valve replacement and single lung transplantation with ECMO support in 1 patient each. Dissection occurred during aortic cannulation or decannulation in 3 patients, during insertion of the antegrade cardioplegia line in 1 patient, during manipulation of the aortic cannula in 1 patient and through direct cannulation of the axillary artery in 1 patient, and during femoral artery cannulation in 1 patient. Replacement of the ascending aorta with resection of the entry side was successfully performed in all 7 patients (median OT time 387 min, ECC 192 min, ACC 101 min, CA 25 min). Patients with iatrogenic aortic dissection have an increased mortality rate and risk factors for bad outcome are as follows: a mean aortic pressure of less than 50 mmHg during the change of arterial cannulation site, advanced age and the time of diagnosis of the dissection.
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T. Fleck (2005) conducted an observational in Intraoperative iatrogenic type A aortic dissection (n=3,000). Open heart surgery was evaluated on Incidence of intraoperative iatrogenic aortic dissection type A. Intraoperative iatrogenic type A aortic dissection occurred in 7 of 3,000 open heart cases (0.23% incidence), with increased mortality linked to low aortic pressure, advanced age, and delayed diagnosis.
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