Key result
Colorectal laparoscopic surgery within an ERAS protocol in elderly patients significantly decreased postoperative IL-6 and CRP levels (p<0.05) and improved prealbumin synthesis compared to standard care.
Why the study?
Does the ERAS protocol reduce surgical stress response and improve nutritional status in elderly patients undergoing elective colorectal laparoscopic surgery?
Population
83 patients aged over 70 years old undergoing elective colorectal laparoscopic surgery, autonomous for…
Comparison
Enhanced Recovery After Surgery protocol. vs Standard of Care program.
Design
RCT, Randomized in two groups within a larger randomized trial
Follow-up
Up to 30 days post-operatively
Authors
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Supports ERAS adoption in elderly colorectal laparoscopy; extends RCT evidence to inflammatory and nutritional biomarkers.
RCT (n=83)
Randomized
No
Does the ERAS protocol reduce surgical stress response and improve nutritional status in elderly patients undergoing elective colorectal laparoscopic surgery?
Absolute Event Rate: 33.5% vs 57.4%
p-value: p=<0.05
The ERAS protocol significantly reduces the surgical stress response and improves postoperative nutritional synthesis and short-term outcomes in elderly patients undergoing elective colorectal laparoscopic surgery.
Mari et al. (2016) conducted an RCT in Elective colorectal laparoscopic surgery (n=83). ERAS protocol vs. Standard program was evaluated on Serum IL-6 levels on postoperative day 1 (pg/ml) (p=<0.05). Colorectal laparoscopic surgery within an ERAS protocol in elderly patients significantly decreased postoperative IL-6 and CRP levels (p<0.05) and improved prealbumin synthesis compared to standard care.
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