Key result
Intravenous paracetamol provided similar visual analogue scale pain scores (p>0.05) but resulted in slightly lower rescue analgesic consumption compared to intravenous ketorolac following day-case gynaecological laparoscopic procedures.
Why the study?
Does intravenous paracetamol improve postoperative analgesia compared to intravenous ketorolac in female patients undergoing day-case gynaecological laparoscopic procedures?
RCT (n=60)
Single-blind
Envelope method
No
Does intravenous paracetamol improve postoperative analgesia compared to intravenous ketorolac in female patients undergoing day-case gynaecological laparoscopic procedures?
p-value: p=>0.05
Intravenous paracetamol provides comparable postoperative analgesia to intravenous ketorolac in day-case gynaecological laparoscopic procedures.
Supports intravenous paracetamol as an effective non-opioid alternative to NSAIDs for postoperative pain;.
Background: Gynaecological laparoscopy is a commonly performed procedure. Providing anesthesiafor this can present a challenge, particularly in the day surgery population. Poor analgesia, nausea andvomiting can cause distress to the patient and increased cost for the health system, because of overnightadmission. In this review we discuss anesthetic and analgesic techniques for day case gynaecologicallaparoscopy. Objectives: Our study is undertaken to compare the efficacy of intravenous paracetamol versus ketorolacfor post operative analgesia after gynaecological day case laparoscopic procedures. Method: Sixty (60) female patients 20 – 40 years of age, of ASA I/II were randomized into two equalgroups of 30 patients each. Patients of group A received intravenous paracetamol 1gm and group Breceived intravenous ketorolac 30mg just after induction of general anesthesia. Postoperative pain wasevaluated by standard 10cm linear visual analogue scale (VAS) at different time intervals. When VAS wasmore than 3 rescue analgesic 50mg tramadol intravenously stat was given. Results: In group A that was paracetamol group and group B that was ketorolac group the visual analoguescale (VAS) almost similar but total analgesic consumption in ketorolac group were slightly higher thanparacetamol group. In paracetamol group 4 patients and in ketorolac group 6 patients required rescueanalgesic dose. Conclusion: Our results indicate that IV paracetamol has better analgesic potency than IV ketorolac forpostoperative analgesia after day case gynaecological laparoscopic procedure. JBSA 2017; 30(2): 90-95
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Shaheen et al. (2017) conducted an RCT in Postoperative pain after gynaecological laparoscopic procedure (n=60). Intravenous paracetamol vs. Intravenous ketorolac 30mg was evaluated on Postoperative pain evaluated by Visual Analogue Scale (VAS) and rescue analgesic consumption (p=>0.05). Intravenous paracetamol provided similar visual analogue scale pain scores (p>0.05) but resulted in slightly lower rescue analgesic consumption compared to intravenous ketorolac following day-case gynaecological laparoscopic procedures.
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