Key result
Cyclooxygenase-2-specific inhibitors appear to be safe and effective alone and in combination with opioids for a variety of surgical procedures, facilitating multimodal postoperative analgesia.
Why the study?
Do COX-2-specific inhibitors improve postoperative analgesia and reduce opioid use in surgical patients?
Population
Surgical patients experiencing postoperative pain
Design
Review
Authors
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Supports multimodal analgesia incorporation now; leaves open confirmation via prospective RCTs.
Do COX-2-specific inhibitors improve postoperative analgesia and reduce opioid use in surgical patients?
COX-2-specific inhibitors offer a safe and effective component of multimodal postoperative analgesia with opioid-sparing benefits.
Stephens et al. (2004) conducted a review in Postoperative pain. Cyclooxygenase 2-specific inhibitors was evaluated. Cyclooxygenase-2-specific inhibitors appear to be safe and effective alone and in combination with opioids for a variety of surgical procedures, facilitating multimodal postoperative analgesia.
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