Key result
Ketorolac can be used in specific pediatric patients after cardiac surgery with minimal risk of bleeding or renal dysfunction with appropriate dosing and duration of use.
Why the study?
Does ketorolac provide safe postoperative pain management in infants and children after cardiac surgery?
Does ketorolac provide safe postoperative pain management in infants and children after cardiac surgery?
Ketorolac is a safe analgesic option with opioid-sparing benefits for selected pediatric patients following cardiac surgery when dosed appropriately.
Supports cautious ketorolac use for select pediatric post-cardiac surgery pain; leaves open need for prospective randomized confirmation.
Ketorolac has been used safely as an analgesic agent for children following cardiac surgery in selected populations. Controversy exists among institutions about the risks involved with this medication in this patient group. This article reviews the current literature regarding the safety of ketorolac for postoperative pain management in children after cardiac surgery. Specifically, concerns about renal dysfunction and increased bleeding risk are addressed. Additionally, the article details pharmacokinetics and potential benefits of ketorolac, such as its opioid-sparing effect. The literature reflects that the use of this medication is not well studied in certain pediatric cardiac patients such as neonates and those with single-ventricle physiology, and the safety of this medication in regards to these special populations is reviewed. In conclusion, ketorolac can be used in specific pediatric patients after cardiac surgery with minimal risk of bleeding or renal dysfunction with appropriate dosing and duration of use.
No takes yet. Share an insight, caveat, or question.
Meredith K. Jalkut (2014) conducted a review in Postoperative pain after pediatric cardiac surgery. Ketorolac was evaluated. Ketorolac can be used in specific pediatric patients after cardiac surgery with minimal risk of bleeding or renal dysfunction with appropriate dosing and duration of use.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: