Fatal Transfusion Reactions From Contamination of Stored Blood by Cold Growing Bacteria

Article1 December 1953FATAL TRANSFUSION REACTIONS FROM CONTAMINATION OF STORED BLOOD BY COLD GROWING BACTERIAALEXANDER R. STEVENS JR., M.D., JAMES S. LEGG, M.S., BERNARD S. HENRY, Ph.D., J. M. DILLE, M.D., WILLIAM M. M. KIRBY, M.D., CLEMENT A. FINCH, M.D.ALEXANDER R. STEVENS JR., M.D., JAMES S. LEGG, M.S., BERNARD S. HENRY, Ph.D., J. M. DILLE, M.D., WILLIAM M. M. KIRBY, M.D., CLEMENT A. FINCH, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-39-6-1228 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe immense value of blood transfusion in anemia and in pathologic states associated with a depleted blood volume is well recognized. For the most effective use of blood, a supply must be immediately available. The natural outgrowth of the clinician's requirements has been the storage of blood in blood banks.While the benefits of transfusion far outweigh the risk, there is a significant hazard in the administration of stored blood. The mortality from blood transfusion has been estimated to be as great as or greater than that from an appendectomy.1The three outstanding dangers are homologous serum hepatitis, reactions due...Bibliography1. Editorial: Abuse of transfusion therapy, New England J. Med. 245: 745, 1951. CrossrefMedlineGoogle Scholar2. BordenHall CWWH: Fatal transfusion reactions from massive bacterial contamination of blood, New England J. Med. 245: 760, 1951. CrossrefMedlineGoogle Scholar3. Whitby L: Blood transfusion, 1949, edited by G. Keynes, Williams and Wilkins Company, Baltimore, p. 467. Google Scholar4. Mollison PL: Investigation of haemolytic transfusion reactions, Brit. M. J. 1: 529, 1943. CrossrefMedlineGoogle Scholar5. 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HeathProvince FKWD: Preservation of human plasma; report of studies with sulfonamide compounds, J. A. M. A. 118: 1034, 1942. CrossrefGoogle Scholar37. SwedbergAlmgren BJ: Pyrogenic hygiene. Survey of prevention of pyrogenic reactions in intravenous therapy in connection with experience gained from clinical testing of plasma preparations, Acta med. Scandinav. 126: 323, 1946. CrossrefGoogle Scholar38. DeAlvarez R: Personal communication. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Seattle, Washington*Received for publication May 18, 1953.From the Departments of Medicine, Microbiology and Pharmacology of the University of Washington School of Medicine and the King County Central Blood Bank.These studies were supported in part by funds accrued from Initiative No. 171. 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RHAME, M.D.Bacterial contamination of platelet concentrates stored at 20 CLe choc transfusionnel par contamination bactérienne du sang conservéProblèmes bactériologiques de la contamination du sang conservéPathophysiology of gram-negative shockNonfermentative gram-negative bacilli of nosocomial interestBlutgruppen und BluttransfusionAufbau und Wirkungsweise bakterieller EndotoxineRed Cell Banking and the Production of a Factor VIII ConcentrateBacteraemic Shock in ObstetricsShock Caused by Gram-negative Microorganisms Analysis of 169 CasesMAX HARRY WEIL, M.D., F.A.C.P., HERBERT SHUBIN, M.D., F.A.C.P., MARJORIE BIDDLE, PH.D.GENERAL PRINCIPLES OF BLOOD TRANSFUSIONToxikologie bakterieller EndotoxineShock in infectious diseases�ber Hyponatri�mie-Syndrome und ihre Analyse durch Elektrolytbestimmung in ErythrocytenProfuse Bleeding due to Transfusion of Contaminated Blood: Report of 5 CasesBacterial Contamination of Preserved Blood and DerivativesDIFFERENTIAL TECHNIQUES AND METHODS OF ISOLATION OF PSEUDOMONASZum Problem der Stickstoffbilanz beim Keimwachstum in StabilisatorenSt�rungen des Wasser- und Elektrolythaushalts bei diuretischer TherapieTherapie der HerzinsuffizienzBlood Transfusion Reactions: Their Causes and IdentificationHeutige Probleme der Bluttransfusion in der chirurgischen PraxisPseudomonas septicemiaAktuelle Fragen der BlutkonservierungBakteriologische Untersuchungen bei bakteriell bedingten TransfusionszwischenfällenNew Technic for Detection of Bacterial Contamination in a Blood Bank Using Plastic EquipmentDANGEROUS CONTAMINANTS IN STORED BLOODBACTERAEMIA AS A CAUSE OF OBSTETRIC SHOCKReport of Routine Tests for Psychrophilic and Mesophilic Contaminants in Banked BloodA Study of Hypotension (Shock) Produced by Meningococcus ToxinAllgemeine Anaesthesiologie 1 December 1953Volume 39, Issue 6Page: 1228-1239KeywordsBacteriaBloodBlood banksBlood transfusionBlood volumeHepatitisMedical servicesMicrobiologyMortalityPharmacology ePublished: 1 December 2008 Issue Published: 1 December 1953 PDF downloadLoading ...