Iatrogenic allogenic case report

We studied 75 patients with a mean age of 36 years, who were injected with modeling substances and developed untoward side effects. About 75% of the patients responded to deflazacort + colchicine; however, 92% suffered a relapse five months later and received azathioprine as immunosuppressant. The most frequent clinical manifestations were: erythema 90%, skin pigmentation 58%, edema 70% and keloids 25%. There were also autoimmune manifestations such as Raynaud's phenomenon, livedo reticularis, psoriasis and arthritis. We have designed a treatment flow chart based on clinical and image improvement . Criteria for severity and lack of response to treatment were increased acute phase reactants, poor response to deflazacort, and personal and/or family history of autoimmune disease.