Key result
Takotsubo syndrome occurred in 6.9% of patients with aneurysmal subarachnoid hemorrhage and was associated with a significantly higher in-hospital mortality rate (32%) compared to those without the syndrome (12%).
Why the study?
Although takotsubo syndrome has been reported in patients with subarachnoid hemorrhage, its incidence and relation to SAH severity were unknown.
Population
245 patients with aneurysmal SAH who underwent both ECG and echocardiography
Comparison
Patients with TTS vs without TTS
Design
Cohort study
Authors
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TTS may guide risk stratification in SAH; leaves open whether targeted intervention improves survival.
Cohort (n=319)
No
Absolute Event Rate: 32% vs 12%
p-value: p=0.018
Takotsubo syndrome is a relatively common complication (6.9%) in patients with aneurysmal subarachnoid hemorrhage and is associated with greater neurological severity and higher in-hospital mortality.
Fujita et al. (2022) conducted a cohort in Aneurysmal subarachnoid hemorrhage (n=319). Takotsubo syndrome vs. No Takotsubo syndrome was evaluated on In-hospital mortality (p=0.018). Takotsubo syndrome occurred in 6.9% of patients with aneurysmal subarachnoid hemorrhage and was associated with a significantly higher in-hospital mortality rate (32%) compared to those without the syndrome (12%).
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