Why the study?
Does high sodium intake alter endogenous natriuretic and digoxin-like immunoreacting activities in human urine compared to low sodium intake?
Does high sodium intake alter endogenous natriuretic and digoxin-like immunoreacting activities in human urine compared to low sodium intake?
The study demonstrates that while high sodium intake increases natriuretic activity in specific urine fractions, digoxin radioimmunoassay is unsuitable for determining endogenous natriuretic activity due to unspecific binding.
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Questions specificity of digoxin radioimmunoassay for endogenous natriuretic activity; leaves open its utility in sodium-balance research.
Kramer et al. (1985) studied this question.
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