Use of estrogen in treatment of familial hemorrhagic telangiectasia

Within a 25 year period, 118 patients with a definitive diagnosis of familial hemorrhagic telangiectasia were treated for recurrent epistaxis. Twenty‐eight patients had dermoplasty but 67 patients received large dose estrogen therapy using ethinyl estradiol. The latter regime proved successful in every patient and the side effects and possible disadvantages of this treatment are considered in detail.